标签:功能 mamicode repeat sed 组成 bsp 图片 data bit
缠绕
上去,就形成核小体了。每个组蛋白肽链都有氮端和碳端两个“尾巴”,这些“尾巴”上的氨基酸可以被加上一些化学基团,即“修饰”。
绿色 = 通常具有转录活性区;
红色 = 通常具有转录抑制区;
黑色 = 其他功能。
Histone mark | Where to find it | Antibody |
H3K4me1 | Active enhancers | ab176877 |
H3K4me3 | Promoters of active genes, bivalent domains | ab8580 |
H3K9ac | Active enhancers and promoters | ab177177 |
H3K27ac | Active enhancers and promoters | ab177178 |
H3K36me3 | Transcribed regions | ab9050 |
H3K79me2 | Transcribed regions | ab177184 |
H3K9me3 | Heterochromatin, satellite repeats, gene-poor regions | ab176916 |
H3K27me3 | Repressed promoters in gene-rich regions, developmental regulators, bivalent domains | ab192985 |
Gamma H2A.X | DNA double-strand breaks | ab81299 |
H3S10P | Whole chromosomes in mitosis | ab177218 |
H4K16ac | Reduced in cancer at repetitive sequences, active genes and enhancers in ESCs. Inhibits formation of high order chromatin structure. | ab109463 |
(From https://www.abcam.cn/epigenetics/histone-modifications-and-where-to-find-them-2)
标签:功能 mamicode repeat sed 组成 bsp 图片 data bit
原文地址:https://www.cnblogs.com/emanlee/p/12342630.html